Thankfully, the Rule of Cool and Rule of Sexy let us mix it up with whatever the Green-Skinned Space Babe's ancestors evolved to store their genomes in. It requires a lot of supporting stuff in the cells, and not even everything on Earth uses it. That's Earth's solution for storing your genome. They'll do it even if there's no reason to think the creature should have DNA in the first place. If they are not physically viable, rest assured there are scientists somewhere who will fiddle with DNA until a hybrid is created. The mother is in a majority of cases the human with the non-human father providing the powers. Demons, elves, aliens, vampires, you name it not only will a human sleep with it, they'll engender children. In fictionland, human beings can conceive children with any intelligent species in existence. This makes it extremely unlikely that creatures of different planets would be able to interbreed, but then again, Mars does need women. In reality, many closely related Earth species share over 99% of their DNA, but cannot produce viable offspring. This is present in most unrealistic fictional genres, including Science Fiction (or, rather Space Opera), fantasy, horror, etc. The results of an Interspecies Romance and/or LEGO Genetics.
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